• Journal of Food & Nutritional Sciences
Review Article

Psoriasis and Nutrition: a focus on Microbiome and Microbiota. A Review

Journal of Food & Nutritional Sciences [2021; 3(1): 18-29]
Received: 24 May 2021, Accepted: 19 June 2021, Published: 25 June 2021

Psoriasis is a chronic inflammatory skin disease. It is also defined as an immune-mediated pathology, with cutaneous and systemic manifestations that has numerous consequences on the quality of life of patients who suffer from it. The etiology of the disease is multifactorial. Psoriasis is common in middle-age people, diffused in western countries without differences between male and female sex. Patients affected by psoriasis show frequently morbidity such as obesity, liver failure, diabetes, hypertension and other cardiovascular diseases. Psoriatic people often have inadequate dietary habits (i.e. poor fiber diet, excessive consumption of sugars or saturated fatty acids) and life-style (i.e. smocking, inactivity). Nutrition plays an important role in the development of psoriasis and it can modulate microbiota and microbiome composition. Especially some nutrients improve positive effects on gut and skin microbiota: ω-3, selenium, fiber, curcumin, tryptophan, vitamin D and zinc. Correct diet habits could influence not only the microbiota composition, but also microbiome composition. It is known that also calorie restriction and low calorie diet can improve the symptomatology and the development of psoriasis. Recent studies have highlighted the crucial role of microbiota in the pathophysiology of chronic inflammatory diseases. Correct food choices may have a crucial role in the pathogenesis of psoriasis.

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