Abstract

This case report details a functional nutrition approach for an 11-year-old male diagnosed with Crohn’s disease and elevated fecal calprotectin levels. The patient initially presented with gastrointestinal pain, bloating, fever, facial swelling, and blood in the stool. Early management emphasized removing inflammatory foods through an eight-to-nine-week elimination diet, followed by gradual transition to a whole-food, modified Paleo pattern. To further support intestinal healing, a targeted supplement protocol was implemented, including serum-derived immunoglobulins, gut barrier-restoring nutrients, probiotics, and high-potency omega-3 fatty acids. Together, these interventions aimed to reduce gastrointestinal inflammation, improve mucosal barrier integrity, and restore microbial balance. Over the following months, the patient experienced significant resolution of gastrointestinal pain, bloating, and facial swelling, along with cessation of rectal bleeding. Fecal calprotectin decreased to 0 µg/g, reflecting normalization of intestinal inflammation. A brief, asymptomatic elevation in early 2025 improved with reinforced dietary consistency, without the need for medication. Throughout two years of follow-up, the patient remained free of gastrointestinal symptoms while avoiding pharmacologic therapy. This case highlights the value of a comprehensive nutrition and supplement-based approach in supporting inflammatory balance and restoring proper gastrointestinal function in pediatric Crohn’s disease.