Abstract

Oral sub mucous fibrosis (OSF) is a high-risk precancerous condition, associated with areca nut habit. The present study was conducted to evaluate the degree of improvement in clinical signs and symptoms of the disease before and after treatment.

Study Design: A pre- and post-treatment evaluation was completed by 80 patients suffering with oral submucous fibrosis. Total patients were divided in 4 groups of 20 each according to type of therapy received. Degree of mouth opening, tongue protrusion, cheek flexibility and burning sensation of mouth were assessed in every group of topical application, Aloe-Vera and Turmeric and/or therapeutic ultrasound.

Setting: All 80 patients with oral submucous fibrosis were selected from outpatient department of Oral Medicine and Radiology, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi (M), Wardha, Maharashtra; India. The study was conducted between January 2016-September 2017.

Results: Significant improvement was seen in all four groups of patients in clinical parameters of degree of mouth opening, tongue protrusion, cheek flexibility and burning sensation of mouth (p-Value=0.0001).

Conclusion: Topical use of Aloe-Vera and Turmeric, in OSF patients proved as safe, non-invasive and effective treatment modalities in improving mouth opening, tongue protrusion, cheek flexibility and reduction in burning sensation. Significant improvement in clinical signs and symptoms were achieved in Aloe- Vera and Turmeric with therapeutic ultrasound.